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. 2018 Aug;10(8):4782-4788.
doi: 10.21037/jtd.2018.07.80.

Health-related quality of life evaluation in patients with non-surgical benign tracheal stenosis

Benoit Jacques Bibas  1 , Paulo Francisco Guerreiro Cardoso  1 , Michele Salati  2 , Helio Minamoto  1 , Mauro Federico Luiz Tamagno  1 , Ricardo Mingarini Terra  1 , Paulo Manuel Pêgo-Fernandes  1
Affiliations

Health-related quality of life evaluation in patients with non-surgical benign tracheal stenosis

Benoit Jacques Bibas et al. J Thorac Dis. 2018 Aug.

Abstract

Background: The primary objective of the study was to evaluate the health-related quality of life (HRQL) of patients with benign post-intubation tracheal stenosis considered as unfit for surgical treatment. Secondary objectives were: (I) to determine if clinical variables (gender, age, total treatment time, and type of tracheal device) could influence HRQL and (II) to compare the results with a normal standardized population.

Methods: Prospective study between August-2014 and December-2016 including patients with tracheal stenosis treated with silicone stents, T-Tubes or tracheostomy. Candidates to airway resection and reconstruction were excluded from the analysis. HRQL was assessed with the SF-36 Health Questionnaire. Backward stepwise regression model analyzed the influence of clinical variables on the SF-36 domains and component summaries. Norm-based results were compared with normative data. Alpha error was 5%.

Results: Ninety-three patients (62M/31F; mean age 38±14 years) were included. Mean overall HRQL in all 8 SF-36 domains was poor. Lowest scores were in the role physical (mean 31.7±38), bodily pain (mean 39.2±35), and role emotional domain (mean 48.7±40). The physical component summary (PCS) was more affected than the mental (P<0.001). Norm-based results indicated that most domains and both physical and mental summaries were below the mean for the USA normative population. Total stenting time significantly influenced the physical (P=0.001) and mental component summaries (P=0.001).

Conclusions: Quality of life of patients with benign tracheal stenosis is severely impaired, and norm-based results indicate that the HRQL is below normative data. Physical and mental discomfort seems to be attenuated by total treatment time.

Keywords: Tracheal stenosis; health-related quality of life (HRQL); tracheostomy.

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Flowchart of the study.
Figure 2
Figure 2
Norm-based scores of the SF-36 health survey for the entire cohort. PF, physical function; RP, role physical; BP, bodily pain; GH, general health; VT, vitality; SF, social function; RE, role emotional; MH, mental health.
See this image and copyright information in PMC

References

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