Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug;10(8):5154-5161.
doi: 10.21037/jtd.2018.07.87.

Surgical embolectomy for acute massive pulmonary embolism: state of the art

Affiliations
Review

Surgical embolectomy for acute massive pulmonary embolism: state of the art

Alessandra Iaccarino et al. J Thorac Dis. 2018 Aug.

Abstract

Massive pulmonary embolism (PE) is a severe condition that can potentially lead to death caused by right ventricular (RV) failure and the consequent cardiogenic shock. Despite the fact thrombolysis is often administrated to critical patients to increase pulmonary perfusion and to reduce RV afterload, surgical treatment represents another valid option in case of failure or contraindications to thrombolytic therapy. Correct risk stratification and multidisciplinary proactive teams are critical factors to dramatically decrease the mortality of this global health burden. In fact, the worldwide incidence of PE is 60-70 per 100,000, with a mortality ranging from 1% for small PE to 65% for massive PE. This review provides an overview of the diagnosis and management of this highly lethal pathology, with a focus on the surgical approaches at the state of the art.

Keywords: Acute pulmonary embolism; cerebrovascular disease; surgical embolectomy.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
PE diagnostic algorithm according to 2014 ESC guidelines. PE, pulmonary embolism. PE, pulmonary embolism; CTA, computed tomography angiography; HypoTN, hypotension.

References

    1. Heit JA. Epidemiology of venous thromboembolism. Nat Rev Cardiol 2015;12:464-74. 10.1038/nrcardio.2015.83 - DOI - PMC - PubMed
    1. Fernandez MM, Hogue S, Preblick R, et al. Review of the cost of venous thromboembolism. Clinicoecon Outcomes Res 2015;7:451-62. 10.2147/CEOR.S85635 - DOI - PMC - PubMed
    1. Klok FA, van Kralingen KW, van Dijk AP, et al. Quality of life in long-term survivors of acute pulmonary embolism. Chest 2010;138:1432-40. 10.1378/chest.09-2482 - DOI - PubMed
    1. Sekhri V, Mehta N, Rawat N, et al. Management of massive and nonmassive pulmonary embolism. Arch Med Sci 2012;8:957-69. 10.5114/aoms.2012.32402 - DOI - PMC - PubMed
    1. Smulders YM. Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: the pivotal role of pulmonary vasoconstriction. Cardiovasc Res 2000;48:23-33. 10.1016/S0008-6363(00)00168-1 - DOI - PubMed

LinkOut - more resources