Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Sep 17:8:36.
doi: 10.1186/s13601-018-0221-z. eCollection 2018.

POLLAR: Impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health (EIT Health) project

Affiliations
Review

POLLAR: Impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health (EIT Health) project

Jean Bousquet et al. Clin Transl Allergy. .

Abstract

Allergic rhinitis (AR) is impacted by allergens and air pollution but interactions between air pollution, sleep and allergic diseases are insufficiently understood. POLLAR (Impact of air POLLution on sleep, Asthma and Rhinitis) is a project of the European Institute of Innovation and Technology (EIT Health). It will use a freely-existing application for AR monitoring that has been tested in 23 countries (the Allergy Diary, iOS and Android, 17,000 users, TLR8). The Allergy Diary will be combined with a new tool allowing queries on allergen, pollen (TLR2), sleep quality and disorders (TRL2) as well as existing longitudinal and geolocalized pollution data. Machine learning will be used to assess the relationship between air pollution, sleep and AR comparing polluted and non-polluted areas in 6 EU countries. Data generated in 2018 will be confirmed in 2019 and extended by the individual prospective assessment of pollution (portable sensor, TLR7) in AR. Sleep apnea patients will be used as a demonstrator of sleep disorder that can be modulated in terms of symptoms and severity by air pollution and AR. The geographic information system GIS will map the results. Consequences on quality of life (EQ-5D), asthma, school, work and sleep will be monitored and disseminated towards the population. The impacts of POLLAR will be (1) to propose novel care pathways integrating pollution, sleep and patients' literacy, (2) to study sleep consequences of pollution and its impact on frequent chronic diseases, (3) to improve work productivity, (4) to propose the basis for a sentinel network at the EU level for pollution and allergy, (5) to assess the societal implications of the interaction. MASK paper N°32.

Keywords: Asthma; Climate change; Pollen; Pollution; Rhinitis; mHealth.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Links between ARIA and MASK for change management. CC Collaborating Center, GA2LEN Global Allergy and Asthma European network, GARD Global Alliance against Chronic Respiratory Diseases, MeDALL Mechanisms of the Development of ALLergy, POLLAR Impact of air POLLution on sleep, Asthma and Rhinitis
Fig. 2
Fig. 2
The POLLAR consortium
Fig. 3
Fig. 3
POLLAR m-health tools
Fig. 4
Fig. 4
MASK questions on sleep
Fig. 5
Fig. 5
The POLLAR knowledge triangle

References

    1. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224–2260. doi: 10.1016/S0140-6736(12)61766-8. - DOI - PMC - PubMed
    1. Cohen AJ, Brauer M, Burnett R, Anderson HR, Frostad J, Estep K, et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet. 2017;389(10082):1907–1918. doi: 10.1016/S0140-6736(17)30505-6. - DOI - PMC - PubMed
    1. Gorr MW, Falvo MJ, Wold LE. Air Pollution and other environmental modulators of cardiac function. Compr Physiol. 2017;7(4):1479–1495. doi: 10.1002/cphy.c170017. - DOI - PMC - PubMed
    1. Li J, Sun S, Tang R, Qiu H, Huang Q, Mason TG, et al. Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis. 2016;11:3079–3091. doi: 10.2147/COPD.S122282. - DOI - PMC - PubMed
    1. Weinreich G, Wessendorf TE, Pundt N, Weinmayr G, Hennig F, Moebus S, et al. Association of short-term ozone and temperature with sleep disordered breathing. Eur Respir J. 2015;46(5):1361–1369. doi: 10.1183/13993003.02255-2014. - DOI - PubMed