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Review
. 2018;6(3):271-275.
doi: 10.1007/s40136-018-0215-3. Epub 2018 Aug 16.

Outcome Measures in Chronic Rhinosinusitis

Fiona Ting  1 , Claire Hopkins  1   2
Affiliations
Review

Outcome Measures in Chronic Rhinosinusitis

Fiona Ting et al. Curr Otorhinolaryngol Rep. 2018.

Abstract

Purpose of review: Chronic rhinosinusitis (CRS) has a significant impact on the quality of life of patients and is a high cost burden to both society and patients. There is a variety of objective and subjective outcome measures that exist to assess the effectiveness of interventions. We aim to review current outcome measures available.

Recent findings: Traditionally, results have focused on objective measures, however, subjective outcome measures are gaining traction as being more important. Outcome measures in chronic rhinosinusitis are currently heterogeneous, thus limiting the impact of meta-analysis of past trial results. The development of a core outcome set may standardize the reporting of outcomes in chronic rhinosinusitis.

Summary: We outline the outcome measures currently available and discuss a proposed core outcome set that may facilitate further value of research on interventions for CRS in adults.

Keywords: Chronic rhinosinusitis; Core outcome sets; Outcome measures; Outcomes; PROMs.

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Conflict of interest statement

The authors declare that they have no competing interests.All reported studies/experiments with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines).

References

    1. Hastan D, Fokkens WJ, Bachert C, Newson RB, Bislimovska J, Bockelbrink A, Bousquet PJ, Brozek G, Bruno A, Dahlén SE, Forsberg B, Gunnbjörnsdóttir M, Kasper L, Krämer U, Kowalski ML, Lange B, Lundbäck B, Salagean E, Todo-Bom A, Tomassen P, Toskala E, van Drunen CM, Bousquet J, Zuberbier T, Jarvis D, Burney P. Chronic rhinosinusitis in Europe—an underestimated disease. A GA(2)LEN study. Allergy. 2011;66:1216–1223. doi: 10.1111/j.1398-9995.2011.02646.x. - DOI - PubMed
    1. Fokkens WJ, et al. European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl. 2012;23:1–298. - PubMed
    1. Hopkins C, Philpott C, Crowe S, Reagan S, Degun A, Papachristou I, Schilder AGM. Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with patients, public and practitioners. Rhinology. 2016;54(1):20–26. doi: 10.4193/Rhin15.199. - DOI - PubMed
    1. Rudmik L, et al. Patient-reported outcome measures for adult chronic rhinosinusitis: a systematic review and quality assessment. J Allergy Clin Immunol. 2015;136(6):1532–1540 e2. doi: 10.1016/j.jaci.2015.10.012. - DOI - PubMed
    1. Simopoulos E, Katotomichelakis M, Gouveris H, Tripsianis G, Livaditis M, Danielides V. Olfaction-associated quality of life in chronic rhinosinusitis: adaptation and validation of an olfaction-specific questionnaire. Laryngoscope. 2012;122(7):1450–1454. doi: 10.1002/lary.23349. - DOI - PubMed

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