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. 2018 Oct;36(10):1927.e1-1927.e2.
doi: 10.1016/j.ajem.2018.06.065. Epub 2018 Jul 2.

AGEP from a dog bite treated with Ibuprofen

Benjamin Chaucer  1 , Abriella Stone  2 , Dustin Whelan  2 , Augustus Demanes  2 , Jacqueline L Fischer  2
Affiliations

AGEP from a dog bite treated with Ibuprofen

Benjamin Chaucer et al. Am J Emerg Med. 2018 Oct.

Abstract

Background: Acute Generalized Exanthematous Pustulosis (AGEP) is a rare dermatologic reaction characterized by an erythematous rash with pustular erosions, fever and leukocytosis. Although most often secondary to antibiotic use, AGEP has also been associated with many drugs. A thorough literature search showed only four previously documented cases of ibuprofen-associated AGEP, and one case of dog bite-associated AGEP.

Case report: We present the case of a 46 year old Caucasian female who developed AGEP after self-treating with ibuprofen for a dog bite.

Conclusion: In the clinical setting this rash is often dramatic and illuminating the causative agent can be a diagnostic challenge. Our case represents a rare cause of AGEP and an important finding for current practitioners.

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