doi: 10.1128/mcb.6.5.1838-1842.1986.
Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system
- PMID: 3023907
- PMCID: PMC367715
- DOI: 10.1128/mcb.6.5.1838-1842.1986
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Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system
Mol Cell Biol.
1986 May.
Abstract
The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.
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