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. 1986 May;6(5):1838-42.
doi: 10.1128/mcb.6.5.1838-1842.1986.

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system

J S Lebkowski, J H Miller, M P Calos

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system

J S Lebkowski et al. Mol Cell Biol. 1986 May.

Abstract

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.

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References

    1. Proc Natl Acad Sci U S A. 1968 Dec;61(4):1306-12 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Dec;82(24):8606-10 - PubMed
    1. J Mol Biol. 1974 May 5;85(1):51-65 - PubMed
    1. Cell. 1974 May;2(1):37-41 - PubMed
    1. Nature. 1975 Mar 20;254(5497):261-2 - PubMed

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