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Review
. 2018 Jan-Dec:12:1753466618801167.
doi: 10.1177/1753466618801167.

Nivolumab for the treatment of Japanese patients with advanced metastatic non-small cell lung cancer: a review of clinical trial evidence for efficacy and safety

Toyoaki Hida  1
Affiliations
Review

Nivolumab for the treatment of Japanese patients with advanced metastatic non-small cell lung cancer: a review of clinical trial evidence for efficacy and safety

Toyoaki Hida. Ther Adv Respir Dis. 2018 Jan-Dec.

Abstract

Programmed cell death (PD)-1 immune checkpoint inhibitors have emerged as promising options for the treatment of multiple cancer types. Nivolumab is a fully human immunoglobulin G4 monoclonal antibody, which inhibits the PD-1 receptor and has been approved in the United States, Europe, and Asia for the treatment of advanced NSCLC. This review focuses on nivolumab's efficacy and safety in the treatment of NSCLC patients in Japan.

Keywords: Japanese; Nivolumab; Non-small cell lung cancer; PD-1 inhibitor.

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Conflict of interest statement

Conflict of interest statement: The author declares that there is no conflict of interest.

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