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. 2018 Sep 24;19(1):343.
doi: 10.1186/s12891-018-2254-9.

Burden of gluteal fibrosis and post-injection paralysis in the children of Kumi District in Uganda

Kristin Alves  1   2 , Norgrove Penny  3 , John Ekure  4 , Robert Olupot  5 , Olive Kobusingye  6 , Jeffrey N Katz  2 , Coleen S Sabatini  7
Affiliations

Burden of gluteal fibrosis and post-injection paralysis in the children of Kumi District in Uganda

Kristin Alves et al. BMC Musculoskelet Disord. .

Abstract

Background: The purpose of this study was to estimate the prevalence of postinjection paralysis (PIP) and gluteal fibrosis (GF) among children treated in a rural Ugandan Hospital.

Methods: We conducted a retrospective cohort study by reviewing the musculoskeletal clinic and community outreach logs for children (age < 18 yrs) diagnosed with either PIP or GF from Kumi Hospital in Kumi, Uganda between 2013 and 2015. We estimated the prevalence as a ratio of the number of children seen with each disorder over the total population of children seen for any musculoskeletal complaint in musculoskeletal clinic and total population of children seen for any medical complaint in the outreach clinic.

Results: Of 1513 children seen in the musculoskeletal clinic, 331 (21.9% (95% CI 19.8-24.1%)) had PIP and another 258 (17.1% (95% CI 15.2-19.0%)) had GF as their diagnosis. Of 3339 children seen during outreach for any medical complaint, 283 (8.5% (95% CI 7.6-9.5%)) had PIP and another 1114 (33.4% (95% CI 31.8-35.0%)) had GF. Of patients with GF, 53.9% were male with a median age of 10 years (50% between 7 and 12 years old). Of patients with PIP, 56.7% were male with a median age of 5 years (50% between 2 and 8 years old).

Conclusion: PIP and GF comprise over 30% of clinical visits for musculoskeletal conditions and 40% of outreach visits for any medical complaint in this area of Uganda. The high estimated prevalence in these populations suggest a critical need for research, treatment, and prevention.

Keywords: Gluteal fibrosis; Post-injection paralysis.

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Conflict of interest statement

Ethics approval and consent to participate

The study was approved by a local Institutional Review Board in Uganda and the Uganda National Council for Science and Technology as well as the senior author’s (CSS) institutional IRB (UCSF). The study was found by all institutions to be exempt from requiring consent.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Case Distribution by Age group. PIP was found more often in children under age 8 while GF more often found in children older than age 8. (*p-value < 0.0001 for association between age and diagnosis, Wilcoxon test)
See this image and copyright information in PMC

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