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. 2018 Oct;16(4):3389-3394.
doi: 10.3892/etm.2018.6623. Epub 2018 Aug 20.

Local injection of dexamethasone helping to prevent lower back pain after epidural delivery analgesia

Zhaoxia Yang  1 , Lanlan Liu  1 , Jinmei Mu  1 , Wenchen Guo  1 , Shunrong Li  2 , Yanyan Jing  3 , Yanyan Liu  1
Affiliations

Local injection of dexamethasone helping to prevent lower back pain after epidural delivery analgesia

Zhaoxia Yang et al. Exp Ther Med. 2018 Oct.

Abstract

This report aims to retrospectively analyze the clinical effect of local pretreatment with dexamethasone (DXMS) on lower back pain after epidural labor analgesia. Patients with epidural labor analgesia treated in People's Hospital of Rizhao from January 2014 to December 2016 were studied. All 368 cases involved were pregnant primipara with full-term single birth. Parturient received injection of DXMS and lidocaine mixture around the epidural puncture point was the observation group (n=188), and parturient received injection of 0.9% sodium chloride and lidocaine mixture around the epidural puncture point was the control group (n=180). The incidence and degree of lower back pain postoperatively in the two groups were evaluated by pain visual analogue scale method. The incidence of lower back pain at 48 h, 72 h after operation in observation group was significantly lower than that in control group (p<0.05). Among patients undergoing one puncture and more than one puncture, the incidence of postoperative lower back pain in the observation group was significantly lower than that in the control group (59.26%) (p<0.05). Among the parturient with spontaneous delivery, the incidence of postoperative lower back pain in the observation group was significantly lower than that in the control group (p=0.028). Among the cesarean section patients, the incidence of pain in observation group was significantly lower than that in control group (p=0.019). At 48 and 72 h after operation, severe pain in the observation group was significantly less than that in the control group (p<0.05). DXMS local pretreatment can significantly reduce the incidence of postoperative lower back pain and the degree of pain after epidural delivery analgesia. DXMS pretreatment in epidural analgesia deserved to be widely used clinically.

Keywords: DXMS; epidural; labor analgesia; lower back pain; pretreatment.

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Figures

Figure 1.
Figure 1.
The incidence of lower back pain at 48 and 72 h after operation in both groups. In the comparison of the incidence of lower back pain at 48 h after operation in the observation group and the control group, *p=0.032; in the comparison of the incidence of lower back pain in the observation group and the control group at 72 h after operation, **p=0.036.
See this image and copyright information in PMC

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