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Case Reports
. 2018 Jul;8(3):e180-e183.
doi: 10.1055/s-0038-1669964. Epub 2018 Sep 14.

A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability

Katherine Kohari  1 , Krista Mehlhaff  1 , Audrey Merriam  1 , Sonya Abdel-Razeq  1 , Olga Grechukhina  1 , Daisy Leon-Martinez  2 , Mert Ozan Bahtiyar  1
Affiliations
Case Reports

A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability

Katherine Kohari et al. AJP Rep. 2018 Jul.

Abstract

Prelabor rupture of the membranes (PROM) near the limit of viability is associated with significant risks for both mother and fetus. Preterm labor, intra-amniotic infection, and placental abruption are the immediate risks to the pregnancy; however, the fetus incurs additional risks related to the sequela of persistent oligohydramnios. Transabdominal intra-amniotic infusions have been studied. Results, suggesting that this intervention may prolong the latency period, and potentially, decrease pulmonary hypoplasia in surviving neonates without evidence of increasing risk of intra-amniotic infection. To our knowledge, the use of antibiotic-infused fluid has not been reported in this clinical scenario. Therefore, we present a case of a patient with PROM before the limit of viability who underwent serial transabdominal amnioinfusions with oxacillin-containing normal saline, which resulted in membrane resealing and neonatal survival with no additional maternal morbidity.

Keywords: periviable PROM; pulmonary hypoplasia; serial amnioinfusion.

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Conflict of interest statement

Conflict of Interest None.

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