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Review
. 2019 Feb;12(1):62-67.
doi: 10.1007/s12265-018-9825-x. Epub 2018 Sep 24.

The Exosome: a New Player in Diabetic Cardiomyopathy

Lichan Tao  1 , Jia Shi  2 , Xiaoyu Yang  1 , Ling Yang  3 , Fei Hua  4
Affiliations
Review

The Exosome: a New Player in Diabetic Cardiomyopathy

Lichan Tao et al. J Cardiovasc Transl Res. 2019 Feb.

Abstract

Diabetic cardiomyopathy (DCM) or diabetes-induced cardiac dysfunction is a direct consequence of uncontrolled metabolic syndrome and occurs worldwide. However, the underlying cellular and molecular mechanisms remain poorly understood. Recently, exosomes have attracted considerable interest for their use as efficient, targeted, and non-immunogenic delivery systems for biological molecules or pharmacotherapies. This review will summarize the fast-developing field of the regulation and function of exosomes in DCM, affording valuable insights and therapeutic opportunities in combatting diabetes-related cardiac disorder for modern human health.

Keywords: Diabetic cardiomyopathy; Exosomes.

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References

    1. J Cardiovasc Transl Res. 2019 Feb;12(1):68-74 - PubMed
    1. J Endocrinol. 2016 Feb;228(2):R57-71 - PubMed
    1. Nat Rev Endocrinol. 2016 Sep;12(9):504-17 - PubMed
    1. J Circ Biomark. 2015 Jul 17;4:7 - PubMed
    1. J Cell Mol Med. 2018 Jan;22(1):141-151 - PubMed

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