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Book

Glycopyrrolate

Ariel Gallanosa  1 , Joshua B. Stevens  2 , Joseph Maxwell Hendrix  3 , Judy Quick  4
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Glycopyrrolate

Ariel Gallanosa et al.
Free Books & Documents

Excerpt

Glycopyrrolate is a muscarinic receptor antagonist and an essential anticholinergic agent in perioperative care and various medical settings. Clinicians use this medication to inhibit salivary and respiratory secretions, achieve antisialagogue effects, and prevent reflex bradycardia during surgical procedures. By targeting muscarinic receptors, glycopyrrolate provides critical support in maintaining physiological stability and optimizing conditions for surgical interventions.

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Conflict of interest statement

Disclosure: Ariel Gallanosa declares no relevant financial relationships with ineligible companies.

Disclosure: Joshua Stevens declares no relevant financial relationships with ineligible companies.

Disclosure: Joseph Maxwell Hendrix declares no relevant financial relationships with ineligible companies.

Disclosure: Judy Quick declares no relevant financial relationships with ineligible companies.

References

    1. Ramalingam R, Senthamizhselvan K, Harichandrakumar KT, Mohan P. Effect of Premedication with Glycopyrrolate on Patient Tolerance and Procedure Outcomes in Patients Undergoing Unsedated Upper Gastrointestinal Endoscopy: A Randomized Placebo-controlled Trial. Euroasian J Hepatogastroenterol. 2023 Jul-Dec;13(2):55-60. - PMC - PubMed
    1. Reisner C, Pearle J, Kerwin EM, Rose ES, Darken P. Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:1965-1977. - PMC - PubMed
    1. Chabicovsky M, Winkler S, Soeberdt M, Kilic A, Masur C, Abels C. Pharmacology, toxicology and clinical safety of glycopyrrolate. Toxicol Appl Pharmacol. 2019 May 01;370:154-169. - PubMed
    1. Albornoz López R, Arias Rico R, Torres Degayón V, Gago Sánchez A. [Formulation of topical glycopyrrolate for hyperhidrosis]. Farm Hosp. 2008 Nov-Dec;32(6):362-3. - PubMed
    1. Fuchs-Buder T, Hofmockel R, Geldner G, Diefenbach C, Ulm K, Blobner M. [The use of neuromuscular monitoring in Germany]. Anaesthesist. 2003 Jun;52(6):522-6. - PubMed

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