Atrial Fibrillation
- PMID: 30252328
- Bookshelf ID: NBK526072
Atrial Fibrillation
Excerpt
Atrial fibrillation is the most common type of cardiac arrhythmia. It is due to abnormal electrical activity within the atria of the heart, causing them to fibrillate. It is characterized as a tachyarrhythmia, which means that the heart rate is often fast. This arrhythmia may be paroxysmal (less than seven days) or persistent (more than seven days). Due to its rhythm irregularity, blood flow through the heart becomes turbulent and has a high chance of forming a thrombus (blood clot), which can ultimately dislodge and cause a stroke. Atrial fibrillation is the leading cardiac cause of stroke. Risk factors for atrial fibrillation include advanced age, high blood pressure, underlying heart and lung disease, congenital heart disease, and increased alcohol consumption. Symptoms vary from asymptomatic to symptoms such as chest pain, palpitations, fast heart rate, shortness of breath, nausea, dizziness, diaphoresis (severe sweating), and generalized fatigue. Although atrial fibrillation may be a permanent disease, various treatments, and risk modifying strategies have been developed to help reduce the risk of stroke in patients that remain in atrial fibrillation. Treatments include anticoagulation, rate control medication, rhythm control medication, cardioversion, ablation, and other interventional cardiac procedures.
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References
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- Mohanty S, Trivedi C, Gianni C, Natale A. Gender specific considerations in atrial fibrillation treatment: a review. Expert Opin Pharmacother. 2018 Mar;19(4):365-374. - PubMed
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- Peters SAE, Woodward M. Established and novel risk factors for atrial fibrillation in women compared with men. Heart. 2019 Feb;105(3):226-234. - PubMed
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