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. 2018 Sep 24;46(6):676-678.
doi: 10.1016/j.devcel.2018.09.005.

Myomaker and Myomerger: It Takes Two to Make One

Nandini N Margam  1 , Roy Duncan  2
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Myomaker and Myomerger: It Takes Two to Make One

Nandini N Margam et al. Dev Cell. .
Free article

Abstract

Muscle-forming myotubes are formed from the cell-cell fusion of myoblasts. In this issue of Developmental Cell, Leikina et al. (2018) provide compelling evidence that myoblast fusion is dependent on a two-component membrane fusion complex of Myomaker and Myomerger, which function in hemifusion and pore formation activity, respectively.

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