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Case Reports
. 2018 Jul 22;10(7):e3023.
doi: 10.7759/cureus.3023.

Age Limit and Radiotherapy Option for Sarcomatoid Carcinoma of the Larynx: A Case Report with Literature Review

Mina Fransawy Alkomos  1 , Michael Rizk  2 , Goubran Eskander  2 , Ahmed Elkheshen  3 , Rupak Mahendhar  4 , Amir Shahbaz  5 , Paria Zarghamravanbakhsh  6 , Phoebe Younan  7 , Nasim Golchin  8 , Issac Sachmechi  9
Affiliations
Case Reports

Age Limit and Radiotherapy Option for Sarcomatoid Carcinoma of the Larynx: A Case Report with Literature Review

Mina Fransawy Alkomos et al. Cureus. .

Abstract

Sarcomatoid carcinomas, also known as spindle cell carcinomas (SPCCs), are rare carcinomas, predominantly developing in the lung. They have lots of features of sarcoma in their histological features. The standard laryngeal carcinoma classification is based on tumor size, lymph node affection, and metastasis (TNM), it is the classification scheme of the American Joint Committee on Cancer Staging (AJCC), and it is used in the same way for stage spindle cell carcinoma (SPCC). We present a case report of a young female along with a literature review of sarcomatoid carcinoma of the larynx.

Keywords: carcinosarcoma; laryngeal sarcomatoid carcinoma; spindle cell carcinomas.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. CT scan findings: A lesion at the glottic level, without any lymphadenopathy.
CT: computed tomography
Figure 2
Figure 2. Histopathology stained with H&E: Spindle cells with short fascicles and pleomorphic nuclei.
Figure 3
Figure 3. Histopathology: Cells eroding mildly dysplastic epithelium.
Figure 4
Figure 4. Histopathology: CD34 positive internal control and negative in tumor cells.
Figure 5
Figure 5. Follow-up by laryngoscope after six months showed no recurrence. Respiration (1) shows the posterior commissure and respiration (2) shows the anterior commissure.
See this image and copyright information in PMC

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