Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
- PMID: 30254815
- PMCID: PMC6150744
- DOI: 10.7759/cureus.3026
Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia
Abstract
Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin's lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegaly and thrombocytopenia. A splenic biopsy confirmed the diagnosis of primary splenic DLBCL. The patient was treated with chemotherapy. This case highlights the importance of considering primary splenic DLBCL with splenomegaly and treating it with chemotherapy and/or splenectomy.
Keywords: hcv; primary splenic dlbcl; r-chop; splenectomy; splenomegaly; thrombocytopenia.
Conflict of interest statement
The authors have declared that no competing interests exist.
Figures
References
-
- Characteristics of primary splenic diffuse large B-cell lymphoma and role of splenectomy in improving survival. Bairey O, Shvidel L, Perry C, Dann EJ, Ruchlemer R, Tadmor T, Goldschmidt N. Cancer. 2015;121:2909–2916. - PubMed
-
- Lenalidomide in diffuse large B-cell lymphomas. [May;2018 ];Chiappella A, Vitolo U. https://www.hindawi.com/journals/ah/2012/498342/ Adv Hematol. 2012 2012:5. - PMC - PubMed
-
- Spleen hematogenous neoplasms - diffuse large B cell lymphoma. [May;2018 ];Mansouri Mansouri. http://www.pathologyoutlines.com/topic/spleendiffuselargeBcell.html 2018
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials