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Case Reports
. 2017 Oct-Dec;6(4):199-201.
doi: 10.1016/j.gmit.2017.03.001. Epub 2017 Apr 17.

Simultaneous bilateral tubal ectopic pregnancy after intracytoplasmic sperm injection and embryo transfer, in a patient with Stage 3 endometriosis

Tariq Baghdadi  1   2 , Bruno Salle  2 , Agnès Bordes  1   2 , Gery Lamblin  1
Affiliations
Case Reports

Simultaneous bilateral tubal ectopic pregnancy after intracytoplasmic sperm injection and embryo transfer, in a patient with Stage 3 endometriosis

Tariq Baghdadi et al. Gynecol Minim Invasive Ther. 2017 Oct-Dec.

Abstract

Introduction: The incidence of extrauterine pregnancy increases to 2-12% following in vitro fertilization -embryo transfer. Several pathogenic theories have been suggested, including abnormal hormonal secretion or exogenous hormones administered in assisted reproductive technology (ART).

Case report: A 32-year-oId nulliparous woman with primary infertility and Stage 3 endometriosis was treated by ART with intracytoplasmic sperm injection and embryo transfer. The patient showed simultaneous bilateral extrauterine pregnancy, managed by laparoscopic salpingectomy.

Discussion: The various possible pathophysiological mechanisms are described, with a review of the literature on simultaneous bilateral extrauterine pregnancy following ART. In pregnancies following ART, ectopic pregnancy should always be screened for by serum β-human chorionic gonadotropin monitoring and transvaginal ultrasound until the implantation site can be confirmed as the incidence is higher than in spontaneous pregnancy. Even if serum β-human chorionic gonadotropin concentration increases normally, possible bilateral ectopic pregnancy should always be investigated if no intrauterine gestational sac can be seen.

Keywords: bilateral ectopic pregnancy; embryo transfer; endometriosis; in vitro fertilization; intracytoplasmic sperm injection.

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Conflict of interest statement

Conflicts of interest: The authors have no conflict of interest relevant to this article.

Figures

Figure 1
Figure 1
Ultrasound image of left side ectopic pregnancy.
Figure 2
Figure 2
Ultrasound image of right ectopic pregnancy.
See this image and copyright information in PMC

References

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