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Case Reports
. 2017 Oct-Dec;6(4):205-206.
doi: 10.1016/j.gmit.2017.06.005. Epub 2017 Jun 26.

Transient elevations of liver enzymes and ovarian vein thrombosis arising after total laparoscopic hysterectomy

Mari Minagawa  1 , Miho Etoh  1 , Masamune Masuda  1 , Koki Kurihara  1 , Mari Fukuyama  1 , Aya Yamamoto  1 , Seiko Katoh  1 , Hiroyuki Fujita  1
Affiliations
Case Reports

Transient elevations of liver enzymes and ovarian vein thrombosis arising after total laparoscopic hysterectomy

Mari Minagawa et al. Gynecol Minim Invasive Ther. 2017 Oct-Dec.

Abstract

Ovarian vein thrombosis in non-pregnant patient is a rare clinical entity. Among 170 patients who underwent total laparoscopic hysterectomy (TLH) in our hospital from December 2011 to December 2015, we have one case of ovarian vein thrombosis (0.0059%). A 42-year-oId woman had a fever of 39 °C on the fourth day after TLH. A blood test revealed elevations of liver enzymes and D-dimer (AST 1157 U/L, ALT 942 U/L and D-dimer >30 μg/L). Computed tomography (CT) scan with intravenous contrast agent demonstrated right ovarian vein thrombosis which caused decline in blood flow to liver and acute liver dysfunction. Low-molecular weight heparin was initiated and liver enzymes reduced rapidly. On the seventeenth day after TLH, CT scan revealed a recanalization of the ovarian vein. We report the clinical outcomes of the case attempted with a small review of the literature.

Keywords: Complications; Liver enzymes; Ovarian vein thrombosis; Total laparoscopic hysterectomy.

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Conflict of interest statement

Conflicts of interest: The authors have no conflicts of interest relevant to this article.

Figures

Fig. 1
Fig. 1
Coronal contrast enhanced CT scan demonstrating dilated right ovarian vein (14 mm) with a long segment filling defect consistent with thrombus (white arrows).
See this image and copyright information in PMC

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