[OPTIMIZATION OF INFUSION THERAPY IN PREOPERATIVE PERIOD IN PATIENTS WITH ACUTE PANCREATITIS]

Abstract

In 180 patients with acute pancreatitis (AP) we investigated the influence of various infu; sion therapy variants for manifestations of multiple organ dysfunction preoperatively. It was established that infusion therapy in patients with mild stage AP (starting APACHE II score 7 points and less) which consists of crystalloid solutions only has the same effect as hyperosmolar/hyperoncotic plasma substitutes (solutions HEK 130/0.4, polyhydric alcohols). The combination infusion therapy with crystalloid solutions HEK 130/0.4 or polyhydric alcohol in patients with severe AP (assessment by APACHE II score 8 point and more) contributed to more rapid stabilization of hemodynamics index, reduce man; ifestations of multiple organ dysfunction and lethality.