Platelet-rich plasma in the foot and ankle
- PMID: 30259330
- PMCID: PMC6220005
- DOI: 10.1007/s12178-018-9522-z
Platelet-rich plasma in the foot and ankle
Abstract
Purpose of review: Platelet-rich plasma has become an increasingly popular treatment option within the orthopedic community to biologically enhance and stimulate difficult-to-heal musculoskeletal tissues. This review evaluates the recent literature on platelet-rich plasma use in the treatment of foot and ankle pathologies.
Recent findings: Recent literature has demonstrated platelet-rich plasma to have a possible benefit in the treatment of Achilles pathology, chronic plantar fasciitis, osteochondral lesions of the talus, ankle osteoarthritis, and diabetic foot ulcers. However, given the lack of standardization of platelet-rich plasma preparations and protocols and the predominance of low-quality studies, no definitive treatment indications exist. Platelet-rich plasma is a promising treatment option, but at present, there is only limited clinical evidence supporting its use in foot and ankle applications.
Keywords: Achilles; Foot and ankle; Orthobiologics; PRP; Platelet-rich plasma.
Conflict of interest statement
Conflict of interest
Both authors declare no conflicts of interest.
Human and animal rights and informed consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
References
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- Andia I., Rubio-Azpeitia E., Martin J.I., Abate M. Biotechnology. 2015. Current Concepts and Translational Uses of Platelet Rich Plasma Biotechnology.
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- Administration FaD. Regulatory Considerations for Human Cells, Tissues, and Cellular and Tissue-Based Products. Minimal manipulation and homologous use. In: Services USDoHaH, editor. Maryland: U.S. Department of Health and Human Services. p. 2017.
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