Review
Predictive markers in lung cancer: a few hints for the practicing pathologist
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- PMID: 30259911
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Review
Predictive markers in lung cancer: a few hints for the practicing pathologist
Pathologica.
2018 Mar.
Abstract
This review article highlights some important points in the evolving area of predictive biomarkers determination in non-small-cell lung cancer toward standardization of testing practices, including EGFR mutations, ALK and ROS1 rearrangements and immunohistochemical expression of PD-L1. Considerations for selecting appropriate populations for molecular testing, and emergence of other targetable molecular alterations are also discussed.
Keywords: ALK; Carcinoma; EGFR; FISH; Immunoistochemistry; Lung; PCR; PDL1; ROS1.
Copyright © 2018 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology.
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