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. 1986 Jul 15;237(2):597-600.
doi: 10.1042/bj2370597.

Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event

R A Galbraith, S Sassa, A Kappas

Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event

R A Galbraith et al. Biochem J. .

Abstract

Exposure of cultured human hepatoma cells (Hep G2) to medium containing 2% (v/v) dimethyl sulphoxide resulted in an approximate doubling in the activity of delta-aminolaevulinate dehydratase, an increase in the haem content and a decreased growth rate; induced enzyme activity was decrease by 50% after treatment with alpha-amanitin. The findings are strikingly similar to those seen in murine Friend-virus-transformed erythroleukaemia cells.

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References

    1. Eur J Cancer Clin Oncol. 1984 Feb;20(2):265-71 - PubMed
    1. Mutat Res. 1983 Mar;108(1-3):437-49 - PubMed
    1. Blood. 1984 Jul;64(1):64-70 - PubMed
    1. Biochem J. 1984 Aug 15;222(1):35-9 - PubMed
    1. J Clin Endocrinol Metab. 1984 Oct;59(4):806-8 - PubMed

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