Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Apr 30;25(2):553-559.
doi: 10.1007/s10068-016-0077-8. eCollection 2016.

Anti-allergic effects and related active constituents of mung bean (Vignaradiatus Linn) sprouts

Li Li  1 , Min-Hui Li  2 , Han-Kun Ren  1 , Yu-Jing Shi  3 , Yin-Mao Dong  1
Affiliations

Anti-allergic effects and related active constituents of mung bean (Vignaradiatus Linn) sprouts

Li Li et al. Food Sci Biotechnol. .

Abstract

The mung bean (Vigna radiata) is an important food crop with preventative effects against human diseases. The anti-allergic activities of mung bean sprouts of different lengths were evaluated by assaying in vivo antipruritic activity and in vitro hyaluronidase inhibitory effects. After 48 h of growth, sprouts were determined to have the best activity and extracted with petroleum (PeF), ethyl acetate (EaF), and n-butanol (nBF). The active EaF extracts were further assayed for in vivo effects on compound 48/80-induced mast cell degranulation and histamine release, as well as the anti-dinitrophenyl (DNP) IgE-induced passive cutaneous anaphylaxis (PCA) reaction. The main chemical constituents were further analyzed by UV spectrophotometry and high-performance liquid chromatography with tandem mass spectrometric detection (LC/MS/MS). EaF significantly protected against compound 48/80-induced mast cell degranulation and histamine release, and PCA. Flavonoids were determined to be the main contributors to the anti-allergic activity of the EaF extracts.

Keywords: LC/MS/MS; anti-allergic activity; antihistamine; mast cell; mung bean sprouts.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Lee SJ, Lee JH, Lee HH, Lee S, Kim SH, Chun T, Imm JY. Effect of mung bean ethanol extract on pro-inflammtory cytokines in LPS stimulated macrophages. Food Sci. Biotechnol. 2011;20:519–524. doi: 10.1007/s10068-011-0072-z. - DOI
    1. Jom KN, Frank T, Engel KH. A metabolite profiling approach to follow the sprouting process of mung beans (Vignaradiata) Metabolomics. 2011;7:102–117. doi: 10.1007/s11306-010-0236-5. - DOI
    1. Tang DY, Dong YM, Ren HK, Li L, He CF. A review of phytochemistry, metabolite changes, and medicinal uses of the common food mung bean and its sprouts (Vignaradiata) Chem. Cent. J. 2014;8:4. doi: 10.1186/1752-153X-8-4. - DOI - PMC - PubMed
    1. Lai F, Wen Q, Li L, Wu H, Li X. Antioxidant activities of water-soluble polysaccharide extracted from mung bean (Vigna radiata L.) hull with ultrasonic assisted treatment. Carbohyd. Polym. 2010;81:323–329. doi: 10.1016/j.carbpol.2010.02.011. - DOI
    1. Wang S, Lin J, Ye M, Ng TB, Rao P, Ye X. Isolation and characterization of a novel mung bean protease inhibitor with anti-pathogenic and antiproliferative activities. Peptides. 2006;27:3129–3136. doi: 10.1016/j.peptides.2006.07.013. - DOI - PubMed

LinkOut - more resources