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. 2016 Mar 31;25(Suppl 1):103-106.
doi: 10.1007/s10068-016-0105-8. eCollection 2016.

Protective effect of resveratrol against pseudorabies virus-induced reproductive failure in a mouse model

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Protective effect of resveratrol against pseudorabies virus-induced reproductive failure in a mouse model

Dingding Su et al. Food Sci Biotechnol. .

Abstract

Resveratrol (RES), a natural polyphenol that is abundant in grapes, exerts anti-inflammatory, anti-oxidative, and antiviral bioactive effects. Protective effects of RES against pseudorabies virus (PrV)- induced reproductive failure were investigated in a mice model. Injection of PrV partially induced stillbirth and abortion, and caused poor growth of progeny. Treatment with RES attenuated the reproductive failure induced by the virus with recovery of the serum progesterone level. RES improved the growth performance of newborn mice. RES can attenuate the reproductive failure induced by PrV in mice.

Keywords: antivirus; pseudorabies; reproductive failure; resveratrol.

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References

    1. Liu FC, Tsai HI, Yu HP. Oxid. Med. Cell. Longev. 2015. Organ-protective effects of red wine extract, resveratrol, in oxidative stress-mediated reperfusion injury. - PMC - PubMed
    1. Liao YF, Zhu W, Li DP, Zhu X. Heme oxygenase-1 and gut ischemia/reperfusion injury: A short review. World J. Gastroenterol. 2013;19:3555–3561. doi: 10.3748/wjg.v19.i23.3555. - DOI - PMC - PubMed
    1. Vardanian AJ, Busuttil RW, Kupiec-Weglinski JW. Molecular mediators of liver ischemia and reperfusion injury: A brief review. Mol. Med. 2008;14:337–345. doi: 10.2119/2007-00134.Vardanian. - DOI - PMC - PubMed
    1. Budak B, Seren M, Turan NN, Sakaogullari Z, Ulus AT. The protective effects of resveratrol and L-NAME on visceral organs following aortic clamping. Ann. Vasc. Surg. 2009;23:675–685. doi: 10.1016/j.avsg.2009.04.003. - DOI - PubMed
    1. Park SY, Park OJ. Modulation of cancer cell proliferation by cell survival signal akt and tumor suppressive energy sensor AMP-activated protein kinase in colon cancer cells treated with resveratrol. Food Sci. Biotechnol. 2010;19:1537–1541. doi: 10.1007/s10068-010-0218-4. - DOI

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