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. 2017 Dec 22;26(6):1613-1623.
doi: 10.1007/s10068-017-0219-7. eCollection 2017.

Biological activities of lactobacilli relevant to cardiovascular health in skim milk

Alaa Abd El-Fattah  1 , Sally Sakr  1 , Samia Mahmoud El-Dieb  1 , Hany Elkashef  1
Affiliations

Biological activities of lactobacilli relevant to cardiovascular health in skim milk

Alaa Abd El-Fattah et al. Food Sci Biotechnol. .

Abstract

In this study, skim milk was fermented using 14 Lactobacillus strains for 16 h at 42 °C or for 48 h at 25 °C. On conclusion of fermentation, the proteolytic, angiotensin converting enzyme-inhibitory (ACE-I), and antioxidant activities as well as the inhibition of thrombin and cholesterol micellar solubility were determined. The results revealed that Lb. paracasei B-4564 exhibited the highest ACE-I activity (68.11%) under the 42 °C for 16 h condition, while Lb. rhamnosus B-1445 demonstrated the highest ACE-I activity (92.23%) under the 25 °C for 48 h condition. Lb. paracasei B-4564 exhibited the highest inhibition rate of thrombin (42.43 and 48.10%) and cholesterol (68.60 and 87.01%) under the 42 °C for 16 h and 25 °C for 48 h conditions, receptively. Lb. rhamnosus B-442 exhibited the highest DPPH radical scavenging activity of 95.63 and 62.89% under the 42 °C for 16 h and 25 °C for 48 h conditions, receptively. Lb. rhamnosus B-1445 demonstrated the highest Fe2+ chelating activity and reducing power under both the tested fermentation conditions.

Keywords: Biological activities; Cardiovascular health; Lactobacilli.

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Conflict of interest statement

Compliance with ethical standardsThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
DPPH radical scavenging of Lactobacillus strains in skim milk. Ascorbic acid serves as a positive control
Fig. 2
Fig. 2
Fe2+ chelating activity of Lactobacillus strains in skim milk. EDTA serves as a positive control
Fig. 3
Fig. 3
Reducing power of Lactobacillus strains in skim milk. Ascorbic acid serves as a positive control
See this image and copyright information in PMC

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