[Terahertz Spectroscopic Investigation of Substrate Materials for Biological Application in the Frequency Range of 1~15 THz]
- PMID: 30264959
[Terahertz Spectroscopic Investigation of Substrate Materials for Biological Application in the Frequency Range of 1~15 THz]
Abstract
As emerging modalities, terahertz time-domain spectroscopy and imaging have been widely applied to investigate the optical properties of different biological tissues. The substrate materials are usually needed for biological spectroscopic measurements. The ultra-broadband and facility in remote sensing of the terahertz air-biased-coherent-detection (ABCD) system mean it is a good potential tool for the spectroscopic study of biological tissues. In this paper, the optical parameters of four typical substrate materials (quartz, high-density polyethylene, teflon and paraffin) are measured using terahertz ABCD spectrometer. The absorption coefficients and refractive indices are presented in the frequency range of 1~15 THz. It is demonstrated that high-density polyethylene and paraffin are good candidates as sample substrate for broadband terahertz biological spectroscopic measurement. However, quartz and teflon which are common substrate materials in narrowband (0.1~3 THz) terahertz system can not be utilized in high terahertz frequency range because they have strong absorption above 5 THz.
Similar articles
-
Ultrabroadband terahertz spectroscopy of a liquid crystal.Opt Express. 2012 Dec 17;20(27):28249-56. doi: 10.1364/OE.20.028249. Opt Express. 2012. PMID: 23263058
-
[The Detection of Ultra-Broadband Terahertz Spectroscopy of InP Wafer by Using Coherent Heterodyne Time-Domain Spectrometer].Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Feb;36(2):322-5. Guang Pu Xue Yu Guang Pu Fen Xi. 2016. PMID: 27209723 Chinese.
-
Ultra-broadband THz time-domain spectroscopy of common polymers using THz air photonics.Opt Express. 2014 May 19;22(10):12475-85. doi: 10.1364/OE.22.012475. Opt Express. 2014. PMID: 24921365
-
[Progress in application of THz-TDS to protein study].Guang Pu Xue Yu Guang Pu Fen Xi. 2008 Oct;28(10):2237-42. Guang Pu Xue Yu Guang Pu Fen Xi. 2008. PMID: 19123380 Review. Chinese.
-
Coherent THz Hyper-Raman: Spectroscopy and Application in THz Detection.Materials (Basel). 2019 Nov 23;12(23):3870. doi: 10.3390/ma12233870. Materials (Basel). 2019. PMID: 31771196 Free PMC article. Review.
Cited by
-
Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique.Sensors (Basel). 2019 Mar 7;19(5):1148. doi: 10.3390/s19051148. Sensors (Basel). 2019. PMID: 30866443 Free PMC article.
MeSH terms
LinkOut - more resources
Research Materials