Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Dec 1;61(6):17617.
doi: 10.1503/cjs.017617.

Surgical management of benign phyllodes tumours of the breast: Is wide local excision really necessary?

Affiliations

Surgical management of benign phyllodes tumours of the breast: Is wide local excision really necessary?

Yiming Qian et al. Can J Surg. .

Abstract

Current guidelines recommending wide local excision (≥ 1 cm margin) for all breast phyllodes tumours regardless of classification are based on retrospective data. Benign phyllodes tumours of the breast are not aggressive. They are often indistinguishable from fibroadenomas on core biopsy and are diagnosed only after excisions without attention to margins. Once the diagnosis is made, the decision to operate and obtain further margins versus wait-and-watch is the dilemma breast surgeons face on a regular basis.

PubMed Disclaimer

Conflict of interest statement

None declared.

References

    1. Kim S, Kim JY, Kim do H, Jung WH, Koo JS. Analysis of phyllodes tumor recurrence according to the histologic grade. Breast Cancer Res Treat. 2013;141:353–63. - PubMed
    1. Lakhani SR, Ellis IO, Schnitt SJ, et al. WHO classification of Tumors of the Breast. 4th edn. IARC Press; Lyon: 2012. pp. 143–7.
    1. NCCN Clinical Practice Guidelines in Oncology. Breast Cancer. Version 2. 2016. [Accessed 14 Aug 2016]. http://www.nccn.org.
    1. Cowan ML, Argani P, Cimino-Mathews A. Benign and low-grade fibroepithelial neoplasms of the breast have low recurrence rate after positive surgical margins. Mod Pathol. 2016;29:259–65. - PubMed
    1. Borhani-Khomani K, Talman ML, Kroman N, et al. Risk of Local Recurrence of Benign and Borderline Phyllodes Tumors: A Danish Population-Based Retrospective Study. Ann Surg Oncol. 2016;23:1543–8. - PubMed

MeSH terms