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Observational Study
. 2019 Mar;33(3):404-410.
doi: 10.1038/s41433-018-0221-1. Epub 2018 Sep 28.

Functional assessment of a new extended depth-of-focus intraocular lens

Giacomo Savini  1 , Nicole Balducci  2 , Claudio Carbonara  3   4 , Scipione Rossi  5 , Manuel Altieri  3   4 , Nicola Frugis  6 , Emilia Zappulla  5 , Roberto Bellucci  7 , Giovanni Alessio  8
Affiliations
Observational Study

Functional assessment of a new extended depth-of-focus intraocular lens

Giacomo Savini et al. Eye (Lond). 2019 Mar.

Abstract

Background/objective: This study aimed to investigate the visual performance of a new extended depth-of-focus intraocular lens (EDOF-IOL).

Subjects/methods: In this multicenter, prospective, observational study, we enrolled 97 patients who underwent cataract surgery or refractive lens exchange with implantation of the Mini Well EDOF-IOL (SIFI, Italy). Patients underwent postoperatively the following examinations between 4 and 8 weeks after surgery: corrected distance visual acuity (CDVA), reading speed with Radner's chart, distance-corrected near visual acuity (DCNVA), defocus curve, contrast sensitivity, and haloes quantitative assessment.

Results: In the whole sample, the mean monocular CDVA and DCNVA were, respectively, 0.02 ± 0.07 logMAR and 0.38 ± 0.15 logRAD (logarithm of the reading acuity determination). In the 67 bilaterally implanted patients, binocular CDVA and DCNVA were better (0.00 ± 0.05 logMAR and 0.26 ± 0.13 logRAD) than the corresponding monocular values (p = 0.02 and p = 0.0002, respectively). Ninety-two percent of patients bilaterally implanted reached a binocular reading speed >80 words per minute at a 0.5 logRAD print size (corresponding to the common book print size). The defocus curves showed that the EDOF-IOL provided increased depth of focus through 2.0 D of defocus, with the best performance at 1.0 and 1.5 D. Contrast sensitivity was within normal limits at all spatial frequencies. The mean visual disturbance index was 0.08 ± 0.12, suggesting low night visual disturbances.

Conclusions: The new EDOF-IOL provided good visual acuity for distance, intermediate, and near vision, with no loss of contrast sensitivity and low risk of night visual disturbances.

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Conflict of interest statement

GS and RB are consultants of SIFI.

Figures

Fig. 1
Fig. 1
Mean values of monocular and binocular reading speed obtained at different print sizes with the Mini Well EDOF-IOL. WPM words per minute, logRAD logarithm of reading acuity determination
Fig. 2
Fig. 2
Monocular defocus curve in patients implanted with the Mini Well EDOF-IOL. The vertical bars represent the standard deviation at defocus. CDVA corrected distance visual acuity
Fig. 3
Fig. 3
Contrast sensitivity of the Mini Well EDOF-IOL. The dotted lines represent the minimum (min) and maximum (max) limits of the normative database. The vertical bars represent the standard deviation at each frequency
See this image and copyright information in PMC

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