[Histopathology and molecular profile of a case of prostatic Ewing sarcoma]

Abstract

We report a case of Ewing sarcoma localized in the prostate gland of a 33-year-old patient without bone or soft tissue involvement. Evidence of EWS and FLI1 gene translocation was detected by fluorescence in situ hybridization (FISH). This is an unusual case with an interesting clinical presentation; indeed, only a few cases have been reported to date and not all have the supporting biological studies now considered essential for the diagnosis.

Keywords: Anatomía patológica; Biología molecular; Ewing sarcoma; Fluorescence in situ hybridization; Hibridación fluorescente in situ; Molecular biology; Pathology; Prostate neoplasms; Sarcoma de Ewing; Tumores prostáticos.