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. 2019 Apr-Jun;51(2):140-143.
doi: 10.1016/j.ram.2018.05.003. Epub 2018 Sep 27.

Atypical hand, foot, and mouth disease caused by Coxsackievirus A6 in Argentina in 2015

Daniel M Cisterna  1 , Cristina L Lema  2 , Leila M Martinez  2 , Elizabeth Verón  3 , Lorena P Contarino  3 , Denise Acosta  4 , María Cecilia Freire  2
Affiliations
Free article

Atypical hand, foot, and mouth disease caused by Coxsackievirus A6 in Argentina in 2015

Daniel M Cisterna et al. Rev Argent Microbiol. 2019 Apr-Jun.
Free article

Abstract

We present two groups of cases of atypical hand, foot, and mouth disease (HFMD) caused by Coxsackievirus A6 (CV-A6) detected in Argentina in 2015. The first group involved 14 patients from Chubut province and the second group affected 12 patients from San Luis province. Molecular analysis of the complete VP1 protein gene revealed the circulation of E2 sublineage, the most predominant worldwide. To our knowledge, this is the first report of CV-A6 infections associated with atypical HFMD in Argentina and South America.

Keywords: Atypical hand, foot, and mouth disease; Coxsackievirus A6; Enfermedad de mano-pie-boca atípica; Enterovirus; Virus Coxsackie A6.

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