Evolution of R plasmids by replicon fusion
- PMID: 3027013
- DOI: 10.1093/jac/18.supplement_c.103
Evolution of R plasmids by replicon fusion
Abstract
The occurrence of plasmid-plasmid fusions in nature and their possible influence on the spread of bacterial drug resistance is considered. Three ways in which replicon fusions can be formed are described; specifically fusions mediated by IS elements, "one-ended transposition" systems derived from Tn3 and like transposons, and pUB2380, a prototype for a new type of transposition. Non-transposition based systems which mediate replicon fusion are also briefly considered.
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