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. 2018 Dec:203:442-446.
doi: 10.1016/j.jpeds.2018.08.019. Epub 2018 Sep 27.

Surfactant Components and Tracheal Aspirate Inflammatory Markers in Preterm Infants with Respiratory Distress Syndrome

Giovanna Verlato  1 , Manuela Simonato  2 , Sonia Giambelluca  3 , Margherita Fantinato  1 , Alessio Correani  4 , Maria Elena Cavicchiolo  1 , Elena Priante  1 , Virgilio Carnielli  4 , Paola Cogo  5
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Surfactant Components and Tracheal Aspirate Inflammatory Markers in Preterm Infants with Respiratory Distress Syndrome

Giovanna Verlato et al. J Pediatr. 2018 Dec.

Abstract

In 93 preterm infants ≤32 weeks of gestational age and 12 control infants, epithelial lining fluid disaturated-phosphatidylcholine, surfactant protein A and B, albumin, and myeloperoxidase activity were assessed after intubation and before exogenous surfactant administration. We found that disaturated-phosphatidylcholine, surfactant protein B, and myeloperoxidase were significantly higher in preterms with chorioamnionitis.

Keywords: chorioamnionitis; disaturated-phosphatidylcholine; preterm newborns; surfactant; surfactant proteins.

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