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. 2018 Sep-Dec;11(3):261-266.
doi: 10.4103/apc.APC_165_17.

Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery

Affiliations

Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery

Supratim Sen et al. Ann Pediatr Cardiol. 2018 Sep-Dec.

Abstract

Background: Native aortic coarctation in young infants can be treated surgically or with balloon angioplasty, although the latter approach remains controversial. We sought to compare midterm outcomes of balloon and surgical coarctoplasty at our center and to review the current practices in literature.

Methods: The study design was a retrospective record review. Patients with coarctation aged <1 year who underwent balloon or surgical coarctoplasty at our center (January 2010-January 2016) with >6-month post-procedure follow-up were studied. Patients with significant arch hypoplasia or interruption, long-segment coarctation, and associated intracardiac lesions were excluded from the study. Clinical, echocardiographic, and procedural details were recorded at initial presentation and follow-up. Need for reintervention was noted.

Results: Out of a total of 75 patients, 28 underwent balloon (Group A) and 47 underwent surgical coarctoplasty (Group B). There were two deaths in Group B (mortality 4.2%) and none in Group A. In neonates, 63.6% of Group A and 17.4% of Group B patients required reintervention (P = 0.007). Beyond the neonatal age, 29.4% of Group A and 41.6% of Group B patients required reintervention (not statistically significant). On univariate analysis, residual coarctation on predischarge echocardiogram was the only significant predictor of reintervention (P = 0.04). On Kaplan-Meier analysis, with neonatal presentation, freedom from reintervention in Group B was significantly higher than Group A (P = 0.028).

Conclusion: In neonates with native aortic coarctation, surgery unequivocally yields better immediate and midterm results and is the preferred treatment modality. In older infants, balloon coarctoplasty has good early and midterm outcomes with acceptable reintervention rates and should be considered a viable alternative to surgery, especially in critical patients with high surgical risk.

Keywords: Balloon angioplasty; coarctation of the aorta; surgical coarctation repair.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Freedom from reintervention for surgery and balloon coarctoplasty (P = 0.526, not significant)
Figure 2
Figure 2
Freedom from reintervention for surgery and balloon coarctoplasty in neonates (P = 0.028, significant)
Figure 3
Figure 3
Freedom from reintervention for surgery and balloon coarctoplasty at 1–12-month age (P = 0.19, not significant)

References

    1. Beekman RH., 3rd . Coarctation of the aorta. In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, editors. Moss and Adams’ Heart Disease in Infants, Children, and Adolescents. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2008. pp. 987–1005.
    1. Rao PS. Transcatheter interventions in critically ill neonates and infants with aortic coarctation. Ann Pediatr Cardiol. 2009;2:116–9. - PMC - PubMed
    1. Lock JE, Bass JL, Amplatz K, Fuhrman BP, Castaneda-Zuniga W. Balloon dilation angioplasty of aortic coarctations in infants and children. Circulation. 1983;68:109–16. - PubMed
    1. Vergales JE, Gangemi JJ, Rhueban KS, Lim DS. Coarctation of the aorta-the current state of surgical and transcatheter therapies. Curr Cardiol Rev. 2013;9:211–9. - PMC - PubMed
    1. Kenny D, Hijazi ZM. Coarctation of the aorta: From fetal life to adulthood. Cardiol J. 2011;18:487–95. - PubMed