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. 1987 Mar;61(3):933-6.
doi: 10.1128/JVI.61.3.933-936.1987.

env-encoded residues are not required for transformation by p48v-myb

J S Lipsick, C E Ibanez

env-encoded residues are not required for transformation by p48v-myb

J S Lipsick et al. J Virol. 1987 Mar.

Abstract

The v-myb oncogene of avian myeloblastosis virus induces acute myeloblastic leukemia in chickens and transforms avian myeloid cells in vitro. The protein product of this oncogene, p48v-myb, is partially encoded by the retroviral gag and env genes. We demonstrated that the env-encoded carboxyl terminus of p48v-myb is not required for transformation. Our results showed, in addition, that a coding region of c-myb which is not essential for transformation was transduced by avian myeloblastosis virus.

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References

    1. Virology. 1975 Nov;68(1):173-81 - PubMed
    1. Virology. 1961 Oct;15:185-99 - PubMed
    1. Nature. 1979 Oct 11;281(5731):452-5 - PubMed
    1. Cell. 1979 Oct;18(2):375-90 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5120-4 - PubMed

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