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Review
. 2017 Apr-Jun;3(2):66-77.
doi: 10.4103/bc.bc_12_17. Epub 2017 Jul 18.

The cerebral circulation and cerebrovascular disease III: Stroke

Ankush Chandra  1 , Christopher R Stone  1 , Xiangnan Du  2 , William A Li  1 , Mitchell Huber  1 , Richard Bremer  1 , Xiaokun Geng  1   2 , Yuchuan Ding  1
Affiliations
Review

The cerebral circulation and cerebrovascular disease III: Stroke

Ankush Chandra et al. Brain Circ. 2017 Apr-Jun.

Abstract

In this paper, our review series on cerebrovascular disease anatomy, physiology, and pathology ends with a thorough discussion of the most significant cerebrovascular pathology: stroke. This discussion proceeds through two layers of organization. First, stroke is divided up into its main etiologic categories (ischemic stroke/transient ischemic attack, hemorrhagic stroke, and ischemic to hemorrhagic transformation). Then, the epidemiological, pathophysiological, clinical, and therapeutic (employed currently as well as emerging) aspects of each etiology are explored; emphasis is placed upon the therapeutic aspects. Finally, once we have covered all aspects of each etiologic category, we end our review with a defense of the thesis that there is much hope for the future of stroke treatment to be derived from familiarity with the literature on emerging therapies.

Keywords: Cerebral circulation; cerebrovascular disease; hemorrhagic stroke; ischemic stroke; ischemic to hemorrhagic transformation; stroke therapies.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Flowchart summarizing the causes and consequences of cerebrovascular diseases
See this image and copyright information in PMC

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