Intrapatient variability in tacrolimus trough levels after solid organ transplantation varies at different postoperative time periods

Itai Gueta^{1

2}, Noa Markovits^{1

2}, Havatzelet Yarden-Bilavsky^{1

2}, Eugenia Raichlin³, Dov Freimark^{2

4}, Jacob Lavee^{2

4}, Ronen Loebstein^{1

2}, Yael Peled^{2

4}

Affiliations

¹ The Institute of Clinical Pharmacology, Sheba Medical Center, Tel Hashomer, Israel.
² Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
³ Division of Cardiology, University of Nebraska Medical Center, Omaha, Nebraska.
⁴ The Olga and Lev Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel.

Free article

Comment

Itai Gueta et al. Am J Transplant. 2019 Feb.

Free article

. 2019 Feb;19(2):611.

doi: 10.1111/ajt.15134. Epub 2018 Oct 29.

Itai Gueta^{1

2}, Noa Markovits^{1

2}, Havatzelet Yarden-Bilavsky^{1

2}, Eugenia Raichlin³, Dov Freimark^{2

4}, Jacob Lavee^{2

4}, Ronen Loebstein^{1

2}, Yael Peled^{2

4}

¹ The Institute of Clinical Pharmacology, Sheba Medical Center, Tel Hashomer, Israel.
² Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
³ Division of Cardiology, University of Nebraska Medical Center, Omaha, Nebraska.
⁴ The Olga and Lev Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel.

No abstract available

Keywords: clinical research/practice; heart transplantation/cardiology; pharmacokinetics/pharmacodynamics; pharmacology; rejection.

Comment on

High tacrolimus trough level variability is associated with rejections after heart transplant.
Gueta I, Markovits N, Yarden-Bilavsky H, Raichlin E, Freimark D, Lavee J, Loebstein R, Peled Y. Gueta I, et al. Am J Transplant. 2018 Oct;18(10):2571-2578. doi: 10.1111/ajt.15016. Epub 2018 Aug 13. Am J Transplant. 2018. PMID: 29989311
Intrapatient variability in solid organ transplantation: Should we make the first move earlier?
Lemaitre F, Tron C, Jezequel C, Verdier MC, Rayar M. Lemaitre F, et al. Am J Transplant. 2019 Feb;19(2):610. doi: 10.1111/ajt.15107. Epub 2018 Sep 24. Am J Transplant. 2019. PMID: 30188607 No abstract available.