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. 2018 Oct 2;320(13):1380-1383.
doi: 10.1001/jama.2018.11187.

Presence of High-Intensity Sweeteners in Popular Cigarillos of Varying Flavor Profiles

Hanno C Erythropel  1 , Grace Kong  2 , Tamara M deWinter  1 , Stephanie S O'Malley  2 , Sven E Jordt  3 , Paul T Anastas  4 , Julie B Zimmerman  1
Affiliations

Presence of High-Intensity Sweeteners in Popular Cigarillos of Varying Flavor Profiles

Hanno C Erythropel et al. JAMA. .

Abstract

This Research Letter evaluates the amount of sugars found in cigarillos by brand.

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr O’Malley reports receiving donated study medications from Pfizer, AstraZeneca, and Novartis; serving as a consultant to and being on the advisory boards of Alkermes, Amygdala, Cerecor, Indivior, Mitsubishi Tanabe, and Opiant; being a member of the American Society of Clinical Psychopharmacology Alcohol Clinical Trials Initiative supported by Alkermes, Amygdala, Arbor Pharmaceuticals, Ethypharm, Lilly, Lundbeck, Otsuka, Pfizer, and Indivior; and serving on a scientific panel for Hazelden Foundation. Dr Jordt reports receiving personal fees and nonfinancial support from Hydra Biosciences and nonfinancial support from GlaxoSmithKline Pharmaceuticals. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Brand, Label Information, and Mean Sweetness of Cigarillo Sections Categorized Into Classic, Sweet, and With Characterizing Flavor
aSweeteners detected (sweetness factor vs table sugar): acesulfame K (200×), glycyrrhizin (50×), neotame (8000×), saccharin (400×), sucralose (600×). Sweeteners not detected in wrappers: aspartame (200×), sorbitol (0.55×); advantame (20 000×), glucose (0.7×), sodium cyclamate (30×), stevioside (300×), sucrose (1×). Spectra available except for glycyrrhizin (m/z 821 [M−H]−), neotame (m/z 380 [M+H]+), and advantame (m/z 458 [M−H]−). bTip was extracted separately from the wrapper and both parts were tested. cSlightly larger than other tested cigarillos, which were 103 to 112 mm long and 10 to 11 mm in diameter. Entourage was 135 mm long and 10 mm in diameter; White Owl Ranger, 160 mm and 12 mm; Phillies Blunt pink, 125 mm and 16 mm. dCalculated as the sweetness content of the outer layer of the product corresponding to the average wrapper thickness (0.2 mm), divided by the surface area of that layer, to yield (mg sugar equivalents)/cm2. eValues reported as mean (95% CI).
Figure 2.
Figure 2.. Statistical Comparison of Cigarillo Sections With Saliva Contact per Flavor Category
The mean (SD) of measured sweetness ([mg sugar equivalents]/cm2)of cigarillo sections with saliva contact (mouth-side one-third or the tip) are shown for the 3 cigarillo flavor categories: classic, 11.65 (15.75); sweet, 10.09 (10.4); and characterizing flavor, 18.62 (20.6). No statistically relevant differences were found among the means (1-way analysis of variance, P = .22) or among Bonferroni multicomparison posttests (classic vs sweet, P > .99; classic vs characterizing flavor, P = .45; sweet vs characterizing flavor, P = .37).
See this image and copyright information in PMC

References

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