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Comparative Study
. 1987 Feb;103(2):163-6.

[Experimental diabetes in mice infected with Coxsackie viruses]

[Article in Russian]
  • PMID: 3028528
Comparative Study

[Experimental diabetes in mice infected with Coxsackie viruses]

[Article in Russian]
E F Bocharov et al. Biull Eksp Biol Med. 1987 Feb.

Abstract

The influence of Coxsackie B4 and AI3 viruses on the pancreas of mice (resistant and susceptible to diabetes) was studied. Glucose intolerance and changes in the synthesis of immunoreactive insulin were detected in all the treated groups of animals. Biochemical changes were more prominent in male DBA/2 mice, infected with Coxsackie B4 virus, in FI (CBA X C57Bl/6) hybrids and in female DBA/2 mice infected with Coxsackie AI3 virus and alloxan.

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