Bronchoscopic Lung Volume Reduction Treatment Using Endobronchial Valves for Emphysema: Emerging Questions

Jorine E Hartman^{1

2}, Lowie E G W Vanfleteren^{3

4

5}, Eva M van Rikxoort⁶, Dirk-Jan Slebos^{7

8}; on behalf of the SOLVE consortium

Affiliations

¹ Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlandsj.hartman@umcg.nl.
² Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlandsj.hartman@umcg.nl.
³ Department of Development and Education, CIRO+, Center of Expertise for Chronic Organ Failure, Horn, The Netherlands.
⁴ Department of Respiratory Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
⁵ COPD Center, Sahlgrenska University Hospital and Institute of Medicine, Gothenburg University, Gothenburg, Sweden.
⁶ Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
⁷ Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
⁸ Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

PMID: 30286446
PMCID: PMC6390450
DOI: 10.1159/000491675

Comment

Bronchoscopic Lung Volume Reduction Treatment Using Endobronchial Valves for Emphysema: Emerging Questions

Jorine E Hartman et al. Respiration. 2018.

. 2018;96(6):588-589.

doi: 10.1159/000491675. Epub 2018 Oct 4.

Authors

Jorine E Hartman^{1

2}, Lowie E G W Vanfleteren^{3

4

5}, Eva M van Rikxoort⁶, Dirk-Jan Slebos^{7

8}; on behalf of the SOLVE consortium

Affiliations

¹ Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlandsj.hartman@umcg.nl.
² Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlandsj.hartman@umcg.nl.
³ Department of Development and Education, CIRO+, Center of Expertise for Chronic Organ Failure, Horn, The Netherlands.
⁴ Department of Respiratory Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
⁵ COPD Center, Sahlgrenska University Hospital and Institute of Medicine, Gothenburg University, Gothenburg, Sweden.
⁶ Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
⁷ Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
⁸ Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

PMID: 30286446
PMCID: PMC6390450
DOI: 10.1159/000491675

No abstract available

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Figures

**Fig. 1**
Example of development of quantitative HRCT software analysis (Thirona, Nijmegen, The Netherlands). a Rendering image of lobar volumes which is used for emphysema scores and air trapping and fissure analysis. b Rendering image of the bronchial tree (right lung) used for airway dimension analysis and pulmonary vasculature, used for vascular volume and lung perfusion.

See this image and copyright information in PMC

Comment on

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.
Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A. Vogelmeier CF, et al. Arch Bronconeumol. 2017 Mar;53(3):128-149. doi: 10.1016/j.arbres.2017.02.001. Epub 2017 Mar 6. Arch Bronconeumol. 2017. PMID: 28274597 English, Spanish.

References

1. Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Arch Bronconeumol. 2017;53:128–149. - PubMed
1. Davey C, Zoumot Z, Jordan S, et al. Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial. Lancet. 2015;386:1066–1073. - PubMed
1. Kemp SV, Slebos DJ, Kirk A, et al. A Multicenter RCT of Zephyr® Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM) Am J Respir Crit Care Med. 2017 DOI: 10.1164/rccm.201707-1327OC. - PubMed
1. Klooster K, ten Hacken NH, Hartman JE, Kerstjens HA, van Rikxoort EM, Slebos DJ. Endobronchial valves for emphysema without interlobar collateral ventilation. N Engl J Med. 2015;373:2325–2335. - PubMed
1. Valipour A, Slebos DJ, Herth F, et al. Endobronchial valve therapy in patients with homogeneous emphysema. Results from the IMPACT study. Am J Respir Crit Care Med. 2016;194:1073–1082. - PubMed

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Bronchoscopic Lung Volume Reduction Treatment Using Endobronchial Valves for Emphysema: Emerging Questions

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Bronchoscopic Lung Volume Reduction Treatment Using Endobronchial Valves for Emphysema: Emerging Questions

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