New Evidence on Carbetocin: Another Arrow in Our Quiver
- PMID: 30287526
- PMCID: PMC6172116
- DOI: 10.9745/GHSP-D-18-00336
New Evidence on Carbetocin: Another Arrow in Our Quiver
Abstract
Carbetocin is more heat stable than oxytocin with at least equivalent efficacy for preventing postpartum hemorrhage. It will certainly be helpful if the supplier can make it available in low-income country settings at a price comparable to oxytocin. But even so, programs will still need oxytocin and other uterotonic medications.
Comment on
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Heat-Stable Carbetocin versus Oxytocin to Prevent Hemorrhage after Vaginal Birth.N Engl J Med. 2018 Aug 23;379(8):743-752. doi: 10.1056/NEJMoa1805489. Epub 2018 Jun 27. N Engl J Med. 2018. PMID: 29949473 Clinical Trial.
References
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- Mundasad S. Revamped drug could save lives of many new mothers – WHO. BBC News. June 28, 2018. https://www.bbc.com/news/world-asia-44617525. Accessed September 10, 2018.
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- Hogerzeil HV, Walker GJA, de Goeje MJ. Stability of Injectable Oxytocics in Tropical Climates: Results of Field Surveys and Simulation Studies on Ergometrine, Methylergometrine and Oxytocin. Geneva: World Health Organization; 1993. http://apps.who.int/medicinedocs/en/d/Js2205e/. Accessed September 10, 2018.
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