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. 2016 Spring:109:60-64.

Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches

Charlotte Simmler  1 , Shao-Nong Chen  1 , Jeff Anderson  1 , David C Lankin  1 , Rasika Phansalkar  1 , Elizabeth Krause  1 , Birgit Dietz  1 , Judy L Bolton  1 , Dejan Nikolic  1 , Richard B van Breemen  1 , Guido F Pauli  1
Affiliations

Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches

Charlotte Simmler et al. HerbalGram. 2016 Spring.

Abstract

The concept of botanical integrity (BI), introduced previously in HerbalGram issue 106, involves the determination of identity, homogeneity, bioactivity, and safety of plant-derived materials designated for human consumption.1 It goes beyond previously established quality control principles. The inaugural article in this series described the three major domains of expertise that are required to assess BI (as noted in Figure 1): botanical examination (botany), phytochemical analysis (chemistry), and biological efficacy and safety assessments (bioactivity, which encompasses the fields of pharmacology and toxicology).

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Figures

Figure 1
Figure 1. Analytical Techniques that Support the Authentication and Phytochemical Characterization of Botanicals
This article focuses on techniques related to botanical examination (botany) and phytochemical analysis (chemistry), which are used to determine the BI of a given plant material. The more recent approaches are highlighted in red, whereas more traditional techniques are in black. (Organoleptic A. = Organoleptic Analysis) *IR (Infrared): This technique can be used on both ground plant material and corresponding extracts.
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References

    1. Simmler C, Chen S, Anderson J, et al. Botanical integrity: the importance of the integration of chemical, biological, and botanical analyses, and the role of DNA barcoding. HerbalGram. 2015;(106):56–58. - PMC - PubMed
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    1. Simmler C, Anderson JR, Gauthier L, et al. Metabolite profiling and classification of DNA-authenticated licorice botanicals. J Nat Prod. 2015;78(8):2007–2022. - PMC - PubMed

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