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Case Reports
. 2018 Sep;9(3):351-354.
doi: 10.1007/s13193-017-0684-8. Epub 2017 Aug 10.

Dermatofibrosarcoma Protuberans of the Breast-a Rare Entity

Suvendu Maji  1 , M J Paul  2 , Supriya Sen  3
Affiliations
Case Reports

Dermatofibrosarcoma Protuberans of the Breast-a Rare Entity

Suvendu Maji et al. Indian J Surg Oncol. 2018 Sep.

Abstract

Dermatofibrosarcoma protuberans (DFSP) represents about 1% of soft-tissue sarcomas with an estimated incidence of 0.8 to 5.0 cases per million per year. This lesion may occur anywhere in the body but more than 50% occur on the trunk, 20% on the head and neck and 30% on the extremities. DFSP of the breast is an extremely uncommon site of presentation. Data regarding DFSP of the breast is limited and mostly in the form of case reports. Clinical presentation is not uniform and may mimic benign skin lesions [1]. However, it typically presents as a nodular cutaneous mass in early or mid-adult life. We herein report a case of DFSP of the breast in a 33-year-old lady who was managed successfully in our institute and review the literature associated with it.

Keywords: Breast; Dermatofibrosarcoma protuberans; Lesion.

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Figures

Fig. 1
Fig. 1
The excised specimen
Fig. 2
Fig. 2
Spindle cells positive for CD34 (in a), negative for S100, desmin and beta catenin. (Areolar smooth muscle positive for desmin in c)
Fig. 3
Fig. 3
Photomicrograph shows spindle cells negative for ER (in e) and PR (in f)
Fig. 4
Fig. 4
Photomicrograph showing a spindle cell lesion (right half) adjacent to breast acini (left half)
Fig. 5
Fig. 5
Photomicrograph showing spindle cells infiltrating between fibroadipose tissues
See this image and copyright information in PMC

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