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. 2018 Oct;11(5):694-703.
doi: 10.1093/ckj/sfy037. Epub 2018 Jun 2.

The metabolomic quest for a biomarker in chronic kidney disease

Robert Davies  1
Affiliations

The metabolomic quest for a biomarker in chronic kidney disease

Robert Davies. Clin Kidney J. 2018 Oct.

Abstract

Chronic kidney disease (CKD) is a growing burden on people and on healthcare for which the diagnostics are niether disease-specific nor indicative of progression. Biomarkers are sought to enable clinicians to offer more appropriate patient-centred treatments, which could come to fruition by using a metabolomics approach. This mini-review highlights the current literature of metabolomics and CKD, and suggests additional factors that need to be considered in this quest for a biomarker, namely the diet and the gut microbiome, for more meaningful advances to be made.

Keywords: biomarkers; chronic kidney disease; diet; metabolomics.

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Figures

FIGURE 1:
FIGURE 1:
Overview of ‘-omics’ approaches.
See this image and copyright information in PMC

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