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. 1987 Mar;55(3):822-4.
doi: 10.1128/iai.55.3.822-824.1987.

An outer membrane protein (porin) as an eliciting antigen for delayed-type hypersensitivity in murine salmonellosis

V Udhayakumar, V R Muthukkaruppan

An outer membrane protein (porin) as an eliciting antigen for delayed-type hypersensitivity in murine salmonellosis

V Udhayakumar et al. Infect Immun. 1987 Mar.

Abstract

The porin, an outer membrane protein of Salmonella typhimurium, was found to be a suitable antigen for eliciting delayed-type hypersensitivity in mouse salmonellosis. Histological examination of the reaction site revealed that the porin was superior to other antigenic preparations in eliciting a typical delayed-type hypersensitivity reaction consisting of mononuclear cell infiltration without polymorphonuclear cell contamination. This study indicates the importance of using a suitable protein antigen from S. typhi for human application.

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