doi: 10.1099/0022-1317-68-3-805.
Human epithelial cell expression of an Epstein-Barr virus receptor
- PMID: 3029307
- DOI: 10.1099/0022-1317-68-3-805
Item in Clipboard
Human epithelial cell expression of an Epstein-Barr virus receptor
J Gen Virol.
1987 Mar.
Abstract
Cultured human epithelium bound and internalized radiolabelled Epstein-Barr virus (EBV) within 1 h of exposure. A similar percentage of cultured cells also were reactive with monoclonal antibodies to the EBV/C3d receptor of B lymphocytes. In cross-sections of fresh frozen, stratified epithelium, receptor expression seemed limited to the less differentiated subpopulation of cells. These findings support the notion of direct infection of epithelial cells by EBV and suggest a viral life cycle in epithelium dependent on the stage of cell differentiation.
Similar articles
-
Epstein Barr virus binding induces internalization of the C3d receptor: a novel immunotoxin delivery system.J Immunol. 1986 Aug 15;137(4):1387-91. J Immunol. 1986. PMID: 3016095
-
Superinfection of epithelial hybrid cells (D98/HR-1, NPC-KT, and A2L/AH) with Epstein-Barr virus and the relationship to the C3d receptor.Cancer Res. 1986 May;46(5):2541-4. Cancer Res. 1986. PMID: 3008992
-
Identification of a human epithelial cell surface protein sharing an epitope with the C3d/Epstein-Barr virus receptor molecule of B lymphocytes.Int J Cancer. 1989 May 15;43(5):786-94. doi: 10.1002/ijc.2910430508. Int J Cancer. 1989. PMID: 2469656
-
[Epstein-Barr virus penetration mechanism to T lymphoblastoid cell lines].Nihon Rinsho. 1997 Feb;55(2):404-8. Nihon Rinsho. 1997. PMID: 9046832 Review. Japanese.
-
EBV's open sesame.Trends Biochem Sci. 1992 Jul;17(7):239-40. doi: 10.1016/0968-0004(92)90400-4. Trends Biochem Sci. 1992. PMID: 1323889 Review. No abstract available.
Cited by
-
Epstein-Barr virus enters B cells and epithelial cells by different routes.J Virol. 1992 Jun;66(6):3409-14. doi: 10.1128/JVI.66.6.3409-3414.1992. J Virol. 1992. PMID: 1316456 Free PMC article.
-
Epstein-Barr virus infection and associated diseases in children. I. Pathogenesis, epidemiology and clinical aspects.Eur J Pediatr. 1992 Oct;151(10):718-25. doi: 10.1007/BF01959075. Eur J Pediatr. 1992. PMID: 1330572 Review.
-
The mechanism of Epstein-Barr virus infection in nasopharyngeal carcinoma cells.Am J Pathol. 1997 May;150(5):1745-56. Am J Pathol. 1997. PMID: 9137098 Free PMC article.
-
Epstein-Barr virus tissue tropism: a major determinant of immunopathogenesis.Springer Semin Immunopathol. 1991;13(2):117-31. doi: 10.1007/BF00201463. Springer Semin Immunopathol. 1991. PMID: 1664981 Review. No abstract available.
-
The pathogenetic basis of viral tropism.Am J Pathol. 1989 Sep;135(3):447-55. Am J Pathol. 1989. PMID: 2675622 Free PMC article. Review. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
