Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Oct:27:10-15.
doi: 10.1016/j.spen.2018.03.002. Epub 2018 Jun 20.

Global Burden of Pediatric Neurological Disorders

Affiliations
Review

Global Burden of Pediatric Neurological Disorders

Charles Richard Newton. Semin Pediatr Neurol. 2018 Oct.

Abstract

Neurological conditions in children represent a significant proportion of the global burden of disease, since they contribute to premature mortality and years lived with disability. The burden of neurological conditions, as measured by the total disability adjusted live years has decreased significantly over the last 25 years (1990-2015), mainly due to the reduction in the mortality, as the years lived with disability has increased slightly. However, in some regions of the world, notably South Asia and sub-Saharan Africa, the burden remains high, driven by the high incidence of prematurity, neonatal encephalopathy and infections of the central nervous system.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Contribution of nondegenerative neurological conditions to GBD as a percentage of DALYs in 2015. (Color version of the figure available online.)
Figure 2
Figure 2
Contribution of nondegenerative neurological disorders to GBD as measured by YLD in 2015 in all ages. (Color version of the figure available online.)
Figure 3
Figure 3
Years lived with disability of children (under 5 years) with neurological disorders from 1990-2015. (Color version of the figure available online.)
Figure 4
Figure 4
Years lived with disability of children (5-14 years) with neurological disorders from 1990-2015. (Color version of the figure available online.)
Figure 5
Figure 5
DALYs per 100,000 in children aged less than 5 years across the regions of the world. Key HI, high income; MENA, Mediterranean and North Africa; sub-Sah Africa, sub-Saharan Africa. (Color version of the figure available online.)
Figure 6
Figure 6
DALYs per 100,000 in children aged 5-14 years across the regions of the world. Key HI, high income; MENA, Mediterranean and North Africa; sub-Sah Africa, sub-Saharan Africa. (Color version of the figure available online.)

References

    1. Murray CJ, Lopez AD. Quantifying disability: Data, methods and results. Bull World Health Organ. 1994;72:481–494. - PMC - PubMed
    1. Murray CJ. Quantifying the burden of disease: The technical basis for disability-adjusted life years. Bull World Health Organ. 1994;72:429–445. - PMC - PubMed
    1. DALYs GBD, Collaborators H. Murray CJ, et al. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition. Lancet. 2015;386:2145–2191. doi: 10.1016/S0140-6736(15)61340-X. - DOI - PMC - PubMed
    1. Erskine HE, Ferrari AJ, Polanczyk GV, et al. The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010. J Child Psychol Psychiatry. doi: 10.1111/jcpp.12186. - DOI - PubMed
    1. Salomon JA, Vos T, Hogan DR, et al. Common values in assessing health outcomes from disease and injury: Disability weights measurement study for the Global Burden of Disease Study 2010. Lancet. 2012;380:2129–2143. doi: 10.1016/S0140-6736(12)61680-8. - DOI - PMC - PubMed

MeSH terms