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Case Reports
. 2018 Sep;9(Suppl 2):S373-S376.
doi: 10.4103/ccd.ccd_461_18.

Childhood Pemphigus Vulgaris: Report of Two Cases with Emphasis on Diagnostic Approach

Varun Surya  1 , Priya Kumar  1 , Sunita Gupta  2 , Aadithya B Urs  1
Affiliations
Case Reports

Childhood Pemphigus Vulgaris: Report of Two Cases with Emphasis on Diagnostic Approach

Varun Surya et al. Contemp Clin Dent. 2018 Sep.

Abstract

Childhood pemphigus vulgaris (CPV) is a rare entity with clinical features and management primarily similar to those of adults; diagnosis may be difficult due to clinical similarity to other disorders such as herpetic gingivostomatitis which is more prevalent in this age group. We report two cases of CPV with emphasis on diagnostic approach. While treating such patients, it is imperative to diagnose CPV in the early stages to prevent serious morbidity and to adjust drug dosage to minimize side effects.

Keywords: Autoimmune bullous disease; Tzanck test; childhood pemphigus vulgaris.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Extensive erosive lesions on the lips, buccal mucosa, and tongue, (b) Acantholytic cells – positive Tzanck test, (c) Direct immunofluorescence showing “fishnet” appearance. ×40, (d) Posttreatment improvement of lesions
Figure 2
Figure 2
(a) Erosive lesions on the labial mucosa and gingiva, (b) Positive Tzanck test, (c) Posttreatment improvement of lesions
See this image and copyright information in PMC

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