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Case Reports
. 2018 Oct 7:2018:bcr2018227574.
doi: 10.1136/bcr-2018-227574.

Dermatomyositis with anti-TIF1-γ antibodies

Axel De Greef  1 , Liliane Marot  1 , Halil Yildiz  2 , Marie Baeck  1
Affiliations
Case Reports

Dermatomyositis with anti-TIF1-γ antibodies

Axel De Greef et al. BMJ Case Rep. .
No abstract available

Keywords: dermatology; general practice / family medicine.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) General aspect. Note the collar of Stokes. (B) Bilateral periorbital heliotrope erythema. (C) Erythematous papules over interphalangeal joints (Gottron’s papules) and mild periungeal erythema. (D) Maculopapular exanthema on patient’s chest (shawl sign). (E-F). Follow-up 5 months after treatment.
Figure 2
Figure 2
(A) Histological analysis showing interface dermatitis with discrete and focal vacuolar modification of basal layer, atrophy of epidermis, oedema of dermis with mild interstitial inflammatory infiltrate, and rare eosinophils. (B). Alcian blue staining puts in evidence mucine accumulation in dermis.
See this image and copyright information in PMC

References

    1. Hill CL, Zhang Y, Sigurgeirsson B, et al. . Frequency of specific cancer types in dermatomyositis and polymyositis: a population-based study. Lancet 2001;357:96–100. 10.1016/S0140-6736(00)03540-6 - DOI - PubMed
    1. Thompson C, Piguet V, Choy E. The pathogenesis of dermatomyositis. Br J Dermatol 2017;357 10.1111/bjd.15607 - DOI - PubMed
    1. Schiffmann ML, Warneke VS, Ehrchen J. Amyopathic dermatomyositis with anti-TIF1 gamma antibodies. J Dtsch Dermatol Ges 2018;16:76–8. 10.1111/ddg.13394 - DOI - PubMed

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