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Review
. 2019 Jan;38(1):93-99.
doi: 10.1007/s10096-018-3399-z. Epub 2018 Oct 8.

Herpes zoster infection and statins: which implications in clinical practice?

Marco Zuin  1   2 , Gianluca Rigatelli  3 , Roberto L'Erario  4 , Giovanni Zuliani  1 , Claudio Bilato  5 , Loris Roncon  6
Affiliations
Review

Herpes zoster infection and statins: which implications in clinical practice?

Marco Zuin et al. Eur J Clin Microbiol Infect Dis. 2019 Jan.

Abstract

Herpes zoster (HZ), which is caused by reactivation of latent varicella zoster virus (VZV), constitutes a major public health concern in both short- and long-term periods. Over the last years, several epidemiological studies have demonstrated that statin use is associated with increased risk of HZ at cerebral level. Because statins are among the most popular and best-selling drugs in western countries, this potential negative pleiotropic effect could have important implications in the daily clinical practice. In the present manuscript, we reviewed the available data on the statin use and the relative risk of HZ infection.

Keywords: Herpes zoster; Immunomodulatory effect; Statin.

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References

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